Arteriosclerotic vessel disease (Intracranial small vessel disease)

Classic cardiovascular disease of the small vessels in the brain. Smoking, age, lifestyle, genetic predisposition etc are all contributing risk factors.  The pathological mechanism behind it is similar to atherosclerosis:

1. Fibrinoid necrosis
2. Lipohyalinosis
3. Microatheroma
4. Microaneurysm formation