Basic Science
- Blood production
- Clotting/coagulation
Core Clinical Problems/Presenting Problems
- Lethargy/Fatigue
- Shortness of breath
- Bruising/Excessive bleeding
- Neck lump
- Splenomegaly
- Pathological fractures
Investigations
- Full blood count
- Haemoglobin
- White cell count and differential
- Platelet count
- Clotting/Coagulation studies
Conditions
- Anaemias
- Systemic causes
- Renal; Endocrine; Rheumatological/Joint; Gastrointestinal; Hepatic
- Deficiencies
- Iron deficiency
- B12 and Folate Deficiencies
- Other megaloblastic anaemias
- Sickle cell disease and trait
- Thalassaemias
- Hereditory Spherocytosis/elliptocytosis
- Enzyme deficiencies
- G6-PD deficiency
- Pyruvate kinase deficiency
- Haemolysis
- Drug-related
- Non-immune
- Haemolytic uraemic syndrome
- Aplastic anaemia
- Primary Idiopathic
- Acquired
- Fanconi’s anaemia
- Systemic causes
- Leukaemias
- Acute myeloid leukaemia
- Acute lymphocytic leukaemia
- Chronic myeloid leukaemia
- B-cell lymphocytic leukaemia
- Hairy cell leukaemia
- Large granular lymphocytic leukaemia
- Lymphomas
- Non-Hodgkin’s lymphoma
- Hodgkin’s lymphoma
- CNS lymphoma
- Myelodysplasia
- Polycythaemia vera
- Erythrocytosis (secondary; relative and idiopathic)
- Essential thrombocytopenia
- Primary myelofibrosis
- Myeloma
- Monoclonal gammopathy of uncertain significance (MGUS)
- Asymptomatic myeloma
- Multiple myeloma
- Disorders of clotting/coagulation
- von Willebrand disease
- Haemophilia A and B
- Haemorrhagic disease of the newborn
- Disseminated Intravascular Coagulopathy (DIC)
- Henoch-Schonlein purpura
- Heparin induced thrombocytopenia +/- thrombosis syndrome
- Hereditable and acquired thrombophilias
- Thrombotic thrombocytopenic purpura (TTP)
- Vessel Wall Abnormalities
- Other
- Blood transfusion reactions
- Neutropenic sepsis
- Graft vs Host disease
- Immunodeficiency syndromes
Managements/Pharmacology
- Haematopoeitic stem cell transplant
- Heparin
- Warfarin
- Blood transfusion
Notes on Medicine/Surgery 