Neonatal Lupus Erythematosus

• Uncommon disease associated with maternal autoantibodies to proteins of Ro/La (SSA/SSB) family (Ro>La)
  • Passive autoimmunity
• The most common features are third degree heart block and cutaneous lupus lesions
  • Other features include leucopenia and hepatitis
• Heart block requires pacing but most other symptoms will resolve within several months

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