Sepsis and SIRS are common and can be a major cause of morbidity and mortality in the critically ill.
- Note that whilst SIRS can be caused by infection, there are many non-infective causes e.g.
- Haematological malignancy
- Surgical procedures etc etc etc.
- If there is a suspected infection + SIRS- SEPSIS 6
- Oxygen (aim for 94-98% unless COPD or sepsis induced hypotension/severe sepsis)
- Fluid resuscitation
- Blood (and other) cultures (e.g. urine, swabs etc)
- IV antibiotics
- Lactate, FBC and Biochem (urgent)
- Monitor urine output (catheterise if appropriate)
- see here for protocol sheet
- IV Amoxicillin, Metronidazole and Gentamicin is protocol in Tayside for infection of unknown source
- Review antibiotic man and investigation results and ammend as necessary if there is a known (/clinically suspected) source